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Immanuel Kant (DE) had proposed much earlier that the Earth formed by condensation (1347, 1348). Williams (US) identified the oldest rocks found on Earth as granite-like rocks called gneiss from the Acasta Gneiss Complex near Great Slave Lake, Northwest Territory, Canada. The Isua Supracrustal rocks in West Greenland are a close second at 3.7 to 3.8 Ga. Lawless (US), Katherine Pering (US), Etta Peterson (US), Jose Flores (US), Cyril Ponnamperuma (LK-US), Isaac R. Cronin (US) examined the Murchison carbonaceous chondritic meteorite and found racemic mixtures of 74 different amino acids: Eight that are present in proteins, eleven with other biological roles (including, quite surprisingly, some neurotransmitters), and fifty-five that have been found almost exclusively in extraterrestrial samples (584, 1423, 1424). Stephen-Sherwood (US), Joseph Eichberg (US), and Dennis E. Randall Gladstone (US), Yuk Ling Yung (US), Akiva Bar-Nun (IL), Sherwood Chang (US), and James F. Wang (US) mixed a porphyrin, AMP, and inorganic phosphate with an imidazole group as a catalyst. Szostak (US) found that the Tetrahymena ribozyme could splice together multiple oligonucleotides aligned on a template strand to yield a fully complementary product strand.
Clair Cameron Patterson (US), George Tilton (US), and Mark Ingham (US) used uranium decay in rocks from Earth and in meteorites that struck Earth to date our solar system at 4.55 billion years old (1860-1862). These rocks were dated using the uranium 235 to lead 207 method (343). Pashley (AU) found membrane-forming non-polar molecules within the Murchison carbonaceous chondritic meteorite (722). Epps (US) reported the synthesis of phospholipids under primitive Earth conditions (1802). Kasting (US) showed that photochemistry in an atmosphere containing carbon dioxide or a mixture of carbon monoxide and carbon dioxide yielded formaldehyde as a major product (165, 1351, 1904). Exposure of the mixture to ultraviolet or visible light resulted in the direct synthesis of ATP (370). Deamer (US) found that fatty acids and glycerol combine spontaneously to produce phospholipids when heated to dryness at 65°C, as they might have been in an evaporating tide pool along a primitive sea (1106). Dworkin (US) and Juan Oró (US) synthesized uridine diphosphate glucose, cytidine diphosphate choline, other phosphorylated metabolic intermediates, the coenzymes adenosine diphosphate glucose (ADPG), guanosine diphosphate glucose (GDPG), and cytidine diphosphoethanolamine (CDP-ethanolamine) under primitive Earth conditions (1598, 1599). Woese (US), Francis Harry Compton Crick (GB), and Leslie Eleazer Orgel (GB-US) suggested that it would have been possible in a pre-DNA world to have a primitive replicating and catalytic apparatus devoid of both DNA and proteins and based solely on RNA molecules, i.e., an RNA world (581, 1797, 2723). This reaction demonstrates the feasibility of RNA-catalyzed RNA replications and supports the RNA world hypothesis (764).
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“Statistically, it’s a little disappointing, but I’m just glad we were able to open the season with a win,” Souders said.
Souders, who only found out he was starting an hour before the game, allowed just three hits and three walks on the day.
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